Dr. Joseph CHOUKROUN
Inventor of the PRF technique
The concept of PRF (Platelet Rich Fibrin) is based on the centrifugation of whole blood without anticoagulants. (J. Choukroun et al. 2001). At the end of the spin, a fibrin clot containing the majority of the platelets and white blood cells is obtained.
This fibrin clot called Platelet Riche Fibrin or PRF will release gradually and growth factors or cytokines in the site (VEGF, PDGF, TGF Beta, Thrombospondin)
The expected objective of these growth factors is to accelerate the soft tissue and bone healing.